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RonaCare® Information

RonaCare® Cyclopeptide-5

Cyclopeptide-5 is the first homodetic cyclic biomimetic peptide for cosmetic application
Cyclopeptide-5 is the first homodetic cyclic biomimetic peptide for cosmetic application

The world’s first homodetic cyclic peptide for cosmetic applications. Designed to fight wrinkles.

Merck’s revolutionary RonaCare® Cyclopeptide-5 smooths wrinkles through innovative molecular design. Cosmetics manufacturers now have access to a highly powerful ingredient with proven efficacy that promotes the skin cells’ anti-aging process. RonaCare® Cyclopeptide-5 - the first of a new peptide generation.

Tailor-made design for superior selectivity

RonaCare® Cyclopeptide-5 is the first homodetic cyclic peptide for cosmetic applications. Due to its smart design RonaCare® Cyclopeptide-5 provides a high selectivity for its biological target – integrins at the RGD binding site. Tailor-made to fit to certain skin cell surface receptors it mimics natural processes of skin communication and repair - unfolding its anti-aging properties. The innovative cyclic molecular design paves the way to anti-aging efficacy in a new dimension.

 

High selectivity of Cyclopeptide-5 due to its customized design
High selectivity of Cyclopeptide-5 due to its customized design

Watch out, wrinkles! In vitro tests show that ...

... Cyclopeptide-5 inhibits harmful degradation enzymes of extracellular matrix (ECM) proteins like collagenase and elastase - retaining the skin’s elasticity and firmness. It also stimulates the stability of the extracellular matrix by activating fibulin, laminin, and collagen. Cyclopeptide-5 gives back to the skin its tensile and compressive strength and firmness – The result is a more youthful, smoother appearance of the skin.

 

High efficacy proven in in vivo tests

During a clinical study, the ingredient was tested on female volunteers aged between 37 to 63. Skin smoothness evaluation according to PRIMOS showed that RonaCare® Cyclopeptide-5 has a skin smoothing activity within a short period of application time

You can trust Cyclopeptide-5 to improve skin’s smoothness and to reduce the appearance of wrinkles. Equipped with the outstanding edge of RonaCare® Cyclopeptide-5, you can create cosmetic products that work with the ultimate in precision. Welcome to a new dimension in effective anti-aging.

Would you like more information? Please contact us. We look forward to hearing from you – and to working with you.

© Merck KGaA, Darmstadt, Germany, 2012

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